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International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts

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International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts

2020; 13(2): 68-68

Published online April 1, 2020 https://doi.org/10.1016/j.jams.2020.03.059

Copyright © Medical Association of Pharmacopuncture Institute.

Chronic Pain Biotypes Predict Differential Analgesic Response to Verum and Sham Acupuncture

Richard Harris

Anesthesiology, University of Michigan, United States

http://creativecommons.org/licenses/by-nc-nd/4.0/

Abstract

Emerging data indicates that not all chronic pain patients with a given diagnosis have the same underlying pathophysiology. This is particularly relevant for the widespread pain condition known as fibromyalgia (FM) wherein existing pharmacologic and non-pharmacologic treatments are suboptimal: only 30-40% of patients have a clinically meaningful reduction in their pain. Varying degrees of pain pathophysiology are also likely relevant for acupuncture as thousands of patients are often needed to determine statistical significance between sham and verum groups in randomized controlled clinical pain trials. I will present data suggesting that quantitative sensory testing and needling sensations obtained at baseline, can be used to identify different biotypes of FM patients that respond differentially to sham and verum acupuncture. More sensitive FM patients respond better to sham acupuncture whereas less sensitive patients respond better to verum. This type of data could improve clinical trial power by selectively identifying the right type of patient at baseline that is likely to respond to the right type of acupuncture treatment. Thus supporting a more personalized approach to the treatment of chronic pain with acupuncture.

Keywords: Pain, Acupuncture, Fibromyalgia

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