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  • Research Paper2019-12-01

    Comparative Analgesia Between Acupuncture and Dipyrone in Odontalgia

    Talita B. de Almeida, Vera L.R. Zotelli, Ronaldo S. Wada, Maria L.R. Sousa*

    Abstract : The aim of this study was to assess whether the effectiveness of acupuncture is similar to the use of analgesics in the management of toothache. The research included 56 volunteers who were divided into 4 groups: Real Acupuncture group, Placebo Acupuncture group, Real Dipyrone group, and Placebo Dipyrone group. The interventions of the study were performed before the dental care. Inclusion criteria were toothache of pulpal origin with pain scale (Visual Analogue Scale) above 4, absence of medication for the pain, and aged over 18 years. The Real Acupuncture volunteers received a session of acupuncture using piercing needles, while volunteers from the Placebo Acupuncture group received an acupuncture session using non-piercing sham needles. Volunteers from the Real Dipyrone group received a dipyrone tablet and the Placebo Acupuncture group received a tablet with no active ingredient. Before any therapeutic intervention, we collected samples from the volunteers’ saliva to analyze the salivary cortisol, the volunteers rated the intensity of their pain using VAS, and we measured their energy level by the Ryodoraku method. After 20 minutes of treatment, all the volunteers’ analysis parameters were collected again. The Real Acupuncture group presented a greater reduction of VAS than the reduction obtained by the Real Dipyrone group (p

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  • Case Report2019-12-01

    Abstract : Cervicogenic somatic tinnitus is a subtype of subjective tinnitus and is defined as tinnitus in which forceful contractions of jaw and neck muscles modulate its psychoacoustic attributes. Various physical therapies have been proposed for the treatment of somatosensory tinnitus although there is no definitive cure for it. This report describes the use of acupuncture in the treatment of a 71-year-old woman with chronic neck pain who suffered from a left-sided tinnitus for 2 years as well. The tinnitus and neck pain severity was rated as 7 and 6, respectively, on a numeric rating scale of 10. On examination, she had restricted cervical range of motion and several myofascial trigger points in cervical muscles. Audiometric tests of the patient were normal. She received trigger point acupuncture of cervical muscles twice per week for 10 sessions. Her tinnitus completely disappeared after the third session and did not return during the 5-year follow-up. Her neck pain intensity also decreased to 1 on the numeric rating scale after 10 sessions. Based on the results of this study, direct trigger point acupuncture of cervical muscles may be beneficial in the treatment of somatic tinnitus with a long-duration effect.

    Abstract
  • Abstract : The common opinion is that in Europe acupuncture was introduced in China at the end of the XVII century. However there are some publications, which describe the similar treatment method in the Stone Age Europe. From ancient to late middle century theoretical and practical aspects of medieval medicine in Europe were very similar to the Tradition Chinese medicine. So it is possible that historical phlebotomy in Europe (bloodletting) played the same role as the acupuncture in the Chinese therapy and they had one scientific source. In this article we are comparing the modern acupuncture with some Bohemian medical tractates (Practica medicinalis by Sigismundus Albicus from 1408–1424, De sanguinis minucione by Cristannus de Prachaticz from 1430). We can see the close relationship between localizations and indications of medieval phlebotomy and modern acupuncture points. 40% of the bloodletting points have close localization with the modern acupuncture points and 57% of their indications are common or very similar. The similarity of two methods may be explained in two ways. First is a common scientific source and intensive interaction and crosscultural transmission of knowledge during medical development in China and Europe up to the beginning of the XV century. This possibility indicates also some linguistic coincidences. On the other hand, both methods could have been developed separately based on common clinical empire and objective neuro-physiological patterns of human body.

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  • Research Paper2019-12-01

    Abstract : To evaluate the feasibility of comparing the effect of the traditional Hijamah and the Asian wet cupping techniques in the management of patients with chronic low back pain (CLBP), a randomized clinical trial comparing traditional and Asian wet cupping techniques for CLBP was conducted in two secondary care hospitals in Saudi Arabia. Seventy eligible participants with CLBP were randomized to receive one session of wet cupping using either Asian technique (34 patients) or traditional Hijamah technique (36 patients). Cupping was performed at four sites of the bilateral bladder meridian (BL23, BL24, and BL25). The numeric rating scale, Present Pain Intensity, and Oswestry Disability Questionnaire scores were measured immediately after intervention, at seven days, and 14 days after intervention. In both groups, there was a significant decrease in the numeric rating scale, Present Pain Intensity, and Oswestry Disability Questionnaire scores, immediately after intervention, at seven days, and 14 days after intervention. However, there was no significant difference between the two groups across all the outcome measures up to 14 days after intervention. The study did not show a superiority of one technique compared with the other. Longer follow-up periods and more than one cupping session may be needed to evaluate the difference, if any, between both the techniques. Trial Registration NCT02012205.

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  • Research Paper2019-08-01

    The Efficacy of Acupuncture in the Treatment of Bell's Palsy Sequelae

    Canan Ertemoğlu Öksüz1*, Ahmet Kalaycıoğlu2, Özlem Uzun1, Şahi Nur Kalkışım1, Nihat Burak Zihni3, Ahmet Yıldırım4, Cavit Boz4

    Abstract : This study was planned to evaluate the effectiveness of acupuncture treatment for the treatment Bell’s palsy sequelae. In this study, forty patients with Bell’s palsy sequelae were randomly allocated to either the acupuncture or the control group. The clinical outcomes before and after treatment were assessed using the following assays: the facial nerve compound motor action potential and HouseeBrackmann (HB) and Sunnybrook (SB) grading scales. Agreement analysis was performed between the SB and HB grading scales. There was significant difference between pretreatment and posttreatment compound motor action potential values of the patients within the acupuncture group (p = 0.036). In pretreatment and posttreatment SB and HB scores, significant differences within the two groups were observed. However, the significance level in the improvement rate in the acupuncture group was higher than that of the control group. General agreement between the SB and HB scores of groups was an acceptable value, and weighted agreement between the scales was a moderate agreement. In this study, we found that acupuncture treatment is effective in improving Bell’s palsy sequelae. Acupuncture can be used as a safe method in the treatment of Bell’s palsy sequelae.

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  • Research Article2021-02-28

    Effect of Remote and Local Acupuncture Points on Periarthritis of Shoulder: A Comparative Study

    Kumaresan Poorna Chandran1,*, Prabu Poorna Chandran2, Naveena Arumugam3, Sendhilkumar Muthappan4

    Abstract : Background: Periarthritis of shoulder is a painful condition of the shoulder, affecting 2-3% of the general population and 20% of diabetic patients. Acupuncture is a widely practiced traditional Chinese medicine. Recent evidence shows that it alleviates shoulder pain with different needling techniques. Objectives: The present study is to compare the efficacy of remote and local points on PAS. Methods: 60 subjects were randomly assigned into two groups, remote acupuncture group (n = 30) and local acupuncture group (n = 30). Both groups were assessed at baseline and at the end of 12 sessions. Shoulder pain and its disability index (SPADI) and (ROM) were measured using goniometer. The intervention was given weekly thrice on alternate days for four weeks with 20 min for each session. Results: The result shows that both remote and local acupuncture points were beneficial in the pain management and rage of motion when compared within the group. The effects of acupuncture at remote acupoints were better than those at local acupoints in SPADI and ROM when compared between two groups. Conclusion: In treatment of periarthritis of shoulder remote acupuncture points may have higher therapeutic value when compared to local points.

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  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS

    Abstract : Strengths of recommendations in clinical practice guidelines (CPGs) are informed by the quality of evidence of efficacy and safety, and transformed into decision making by balancing generalizability, availability, affordability, acceptability, direct and indirect costs and the values and preferences of patients, providers and policy makers. There is a paucity of evidence for many Traditional, Complementary and Integrative Medicine (TCIM) interventions and services, however their recognition in CPGs contributes to co-ordinated continuity of care across multiple healthcare settings and enhances evidence-based, person-centered clinical effectiveness and policy decisions. CPG development is a complex process that includes multidisciplinary panels of experts and stakeholder consultation. TCIM experts are required to articulate modifying factors and inform PICO questions, to accurately inform the inclusion of TCIM in CPGs. This scoping and evidence review informed the updated CPG: Deciding palliative and end of life care for people with diabetes. Method A two phased literature search included 1. a scoping review and 2. a rapid systematic review of evidence. Electronic databases and grey literature were systematically searched to clarify modifying factors and shortlist 20 TCIMs of a rapid systematic review of efficacy. Results 209 studies clarified seven key modifying factors including patient preferences; routine use; safe TCIMs for co-morbidities; simultaneous acting TCIMs; high quality evidence of effectiveness or ineffectiveness; risks and logistic feasibility. Evidence-based strong recommendations of the CPG included when to start or continue a TCIM intervention, refer to an appropriately qualified TCIM practitioner and when to stop a TCIM intervention or service. Conclusion Inclusion of TCIM in CPGs requires a systematic approach to the quality of evidence, balanced against patients' values, benefits and harms, available resources, feasibility of the intervention, acceptability by stakeholders and effect on health equity. Inclusion of TCIM in CPGs can provide succinct high-level recommendations that facilitate patient centred evidence-based care and accurately inform evidence-based policy.

    Abstract
  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS
  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS

    Abstract : Cannabis sativa L. has long been used as an agricultural commodity for fiber and seed oil production. Recently, these plants have garnered public attention due to their therapeutic potential. Cannabidiol (CBD) is one of the naturally occurring cannabinoids in the cannabis plant. CBD is a potent regulator of neurotransmission, indirectly modulating a number of neurological and psychiatric responses by interacting with both cannabinoid receptors (CB1 and CB2) and non-CB receptors (e.g., vanilloid-type 1 receptor, 5-hydroxytryptamine (5-HT), and γ-aminobutyric acid (GABA)). Unlike Δ-9-tetrahydrocannabinol (THC), CBD has no psychoactivity, exhibiting no effects indicative of any potential for abuse or dependence. Over the past decades, CBD has been studied for its therapeutic potential as an anti-inflammatory, antioxidant, neuroprotectant, anticonvulsant, anti-panic, anxiolytic, antidepressant, analgesic, anti-tumoral agent, and anti-psychotic substance. In mice infected with the Dravet syndrome, CBD effectively reduced seizures and autistic-like social behaviors. The effects CBD exhibited were mediated through antagonism of the non-CB receptor, G protein-coupled receptor (GPR) 55. Additionally, recent clinical studies have also supported the mouse study and found that CBD tremendously reduced the frequency and severity of chronic seizures while increasing the quality of life in humans with epilepsy. CBD is not only limited to the treatment of epilepsy but also shows efficacy for a wide array of different human disorders, ranging from cancer to chronic neuropathic pain, which reflects the broad spectrum of molecular targets. With the legalization of cannabis for medicinal purposes globally, an increase in pre-trials and clinical trials are anticipated and should facilitate exploration of the unknown therapeutic functions of phytocannabinoids.

    Abstract

Journal Info

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
February, 2021
Vol.14 No.1

pISSN 2005-2901
eISSN 2093-8152

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  • Research Article2020-06-01

    Effectiveness of Manual and Electrical Acupuncture for Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial

    Josielli Comachio 1, *, Carla C. Oliveira 1, Ilton F.R. Silva 1, Mauricio O. Magalhães 1, 2, Amélia P. Marques 1

    Abstract : Background: Low back pain is a common condition that can be effectively treated by acupuncture. However, several treatment point prescriptions and further electrical needle stimulation (i.e., local acupoints, distal acupoints, and sensitized acupoints) may be used. There is an implicit yet unexplored assumption about the evidence on manual and electrical stimulation techniques. Objective: The present study aims to identify effectiveness of electroacupuncture (EA) and manual acupuncture (MA) on pain and disability in patients with chronic nonspecific low back. Methods: This study is a randomized controlled clinical trial. Sixty-six patients between 20 and 60 years of age with non-specific chronic low back pain experiencing low back pain lasting for at least the previous three months and ≥3 points on a 10 numerical analogic scale. Patients diagnosed with chronic LBP were assigned to receive either 12 sessions of MA or EA. The primary outcomes measurements were pain intensity on Numeric Rating Scale and disability by Roland Morris Disability Questionnaire. Results: The participants reported improvements post-treatment to pain intensity and disability respectively; however, no differences between groups were observed. Regarding the secondary outcomes, we observed a between-group difference only for kinesiophobia in favor of the manual acupuncture group (difference = -4.1 points, 95% CI = -7.0 to -1.1). The results were maintained after 3 months of follow-up. Conclusion: The study provides evidence that EA is not superior to MA treatment. Both therapies had similar efficacy in reducing pain and disability for chronic nonspecific low back pain.

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  • Research Article2020-06-01

    Effect of Transcutaneous Electrical Nerve Stimulation on the Pain Intensity During Insertion of Needle in Patients Undergoing Spinal Anesthesia: A Randomized Controlled Study

    Javad AminiSaman 1, Hasan A. Karimpour 1, Behzad Hemmatpour 2, Saeed Mohammadi 1, Saeed Darvishi 3, Rasool Kawyannejad 4, 5, *

    Abstract : Background and objectives: Needle insertion pain during spinal anesthesia is an unpleasant experience for patients. This study aimed to investigate the effects of Transcutaneous Electrical Nerve Stimulation (TENS) on the pain intensity during the insertion of spinal needles in patients undergoing spinal anesthesia. Materials and methods: In a double-blind clinical trial, 60 candidates for elective Trans Ureteral Lithotripsy surgery under spinal anesthesia were randomly divided into intervention and control groups. The electrodes of the TENS device were placed in the space between L3-L4 and L5-S1 vertebrae. The intensity of pain during insertion of the spinal needle by Visual Analog Scale and the frequency of attempts were recorded. Results: The mean age of the study samples was 34.26 ± 5.07 and 32.8 ± 5.28 in the control and intervention group, respectively. The pain intensity during insertion of spinal needles was less significant in the intervention group compared to the control group (p = 0.001). The number of attempts to insert the spinal needle between the two groups was not statistically significant (p = 0.51). The duration of spinal anesthesia implementation procedure by physician in the intervention group was significantly shorter than that of the control group (p = 0.001). Conclusion: The use of TENS effectively reduced the pain of spinal needle insertion. Considering these beneficial effects, it is suggested that this procedure be used to relive pain in patients with spinal anesthesia.

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  • Research Article2020-10-01

    The Effect of Laser Acupuncture on Spasticity in Children with Spastic Cerebral Palsy

    Dian E. Putri 1, *, Adiningsih Srilestari 1, Kemas Abdurrohim 1, Irawan Mangunatmadja 2, Luh K. Wahyuni 3

    Abstract : Background: Spasticity in cerebral palsy is one of the most common disabilities of children in developing countries. Objectives: The objective of this study was to determine the efficacy of laser acupuncture on spasticity in children with spastic cerebral palsy. Methods: This clinical trial was conducted on 60 patients with spastic cerebral palsy at 2 to 10 years. The patients were categorized into two groups: the control group and treatment group. Laser acupuncture was applied on GV20, GV14, LI4, GB34, and LR3 (power 50 mW, 785 nm, 1 Joule, 40 seconds) three times a week for 12 sessions in the treatment group and placebo laser acupuncture on the same points in the control group. The spasticity was measured using the Modified Ashworth Scale before and after complete sessions. Results: The results showed that there was a significant reduction in the Modified Ashworth Scale score in the treatment group compared with the control group (p = 0.003). Conclusions: This study suggest that laser acupuncture on GV20, GV14, LI4, GB34, and LR3 can reduce spasticity for children with spastic cerebral palsy.

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  • Research Article2020-08-01

    Abstract : Background: Osteoarthritis is the most common type of arthritis. Depression, anxiety, and stress are associated with knee osteoarthritis. Objectives: The aim of the study was to check the effectiveness of acupressure therapy with pharmacological treatment on pain, depression, anxiety, and stress in patients with knee osteoarthritis and to assess the effect of pain improvement on psychological health. Methods: Eligible 212 patients with knee osteoarthritis were divided into two groups (intervention and control group). The intervention group (n = 106) received acupressure therapy in combination with pharmacological treatment, whereas the control group (n = 106) continued pharmacological treatment only. Pain and psychological symptoms were measured using the visual analog scale and Depression Anxiety Stress Scale-21. Pearson's correlation was used to check the effect of pain improvement on psychological health. Results: Patients of both groups reported severe pain initially. On analyzing the results after completion of the study, it was found that patients in the intervention group scored better on the pain scale (p < 0.001) and DASS-21 (p ≤ 0.0001). However, it may be noted that reduction in the DASS-21 score was not found to be significant for the control group (p = 0.08). Pearson's correlation coefficients value ranged from 0.231 to 0.412 for DASS-21 (p < 0.05). Conclusions: On analysis, it can be concluded that acupressure can be used as add-on therapy in combination with conventional treatment (pharmacological treatment), which may assist in pain reduction. The reduction in pain directly contributes to improvement in the physiological wellness among patients with knee osteoarthritis.

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  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01

    Abstract : Purpose As science and medicine evolves, the average life span of mankind is rapidly being extended. The growing population of the elderly and interest towards well-being is stimulating growth of the complementary medicine market. Acupuncture is one of the most popular treatments to the patients seeking complementary medicine. As patient population receiving acupuncture increases worldwide, needs for a standardized clinical guideline is growing. Among the many diseases treated by acupuncture, musculoskeletal disorders rank the top. The objective of this study is to establish Korean Medicine clinical guideline for non-specific chronic low back pain. Methods A task force team to establish the guideline was composed. Literature review was done in order to search for evidence of safety and efficacy of acupuncture and other Korean Medicine treatments. A survey was done in order to find out how Korean medical doctors derive pattern identification for acupuncture and herbal prescriptions in treating non-specific chronic low back pain. Then, based on the results of literature review and survey, a conference meeting of experts was held. Through the Delphi method, a draft of the acupuncture clinical guideline for non-specific chronic low back pain was established. Now the review board, composed of experts of musculoskeletal disorders, public health, statistics, and representatives of patients are modifying the draft. Results Evidence of safety and efficacy of acupuncture treatment for musculoskeletal disorders was established. A standard or pattern identification was derived. A draft of Korean Medicine clinical guideline for non-specific chronic low back pain was established. Conclusions More rigorous, well designed and large scaled RCTs are in need to improve the quality and make modifications this clinical guideline.

    Abstract
  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01

    Abstract : Objectives This study is related to stimulate of mesenchymal stem cell (MSC) release into blood by use of electroacupuncture (EA) at specific acupoints. Methods EA was performed in rats using LI4, LI11, GV14, and Baihui (rats). Results Through some methods such as functional magnetic resonance imaging (fMRI) and pharmacological disinhibition of hypothalamus, the activation of the sympathetic nervous system resulted in a release of MSC into the circulation. In addition, EA treatment in rats that had partial rupture of the Achilles tendon induced analgesia, increasing interleukin-10 levels and remodeling. Conclusion EA as low risk, and very effective method should be used to support the repair of tissue wound by increasing of the circulating MSC.

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