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  • Abstract : Equine acupuncture and herbal medicine are increasingly popular and have been anecdotally used in the treatment of a number of conditions. There is, however, a lack of data on the most commonly treated conditions in horses. The medical records of 164 horses presented exclusively for acupuncture and herbal therapy over a three-year period from October 2012 to October 2015 were evaluated from a mixed animal integrative medicine service at a veterinary academic teaching hospital. Horses were presented primarily for musculoskeletal conditions (62.0%), gastrointestinal disorders (9.5%), and anhydrosis (6.1%). Nearly half of all treated horses were geldings, and the mean age of treatment was 10.7 ± 6.5 years. The most common breeds were Warmbloods (28.2%), Quarter horses (20.2%), Thoroughbreds (17.8%), and Arabians (8.0%). Treatments included acupuncture (90.2%), herbal supplements (79.8%), electroacupuncture (69.9%), B12 injections (pharmacoacupuncture, 29.4%), or administration of autologous blood at acupuncture points (hemoacupuncture, 8.0%). Thirty-eight (38) different herbal formulas were recommended during the study period. Horses that were not provided herbal recommendations were more likely to present with gastrointestinal complaints (odds ratio = 11.2). Sex, breed, and presenting complaint had no or minimal impact on the types of treatments performed during the visit. However, data regarding patient characteristics and presenting complaints provide novel information which can be used to design prospective clinical trials.

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  • Abstract : The present case study illustrates the case of a 47-year-old female (Ms X) with primary progressive Multiple Sclerosis (MS) who presented with central post-stroke pain (CPSP) over her left shoulder and underwent acupuncture treatment (AT) since she appeared irresponsive to conventional treatment. The aim of this case study is to explore the effectiveness of acupuncture as a complimentary treatment in improving central neurogenic pain in MS patients affected by CPSP. AT lasted six weeks, some modification of the conventional AT points was required to ensure continuity and safety of the treatment plan. In fact, Ms X suffered from gingivitis that led to hypersensitivity of her left upper limb (UL) to acupuncture needling; moreover, she experienced sensation loss in her legs as a result of post-stroke complications. The outcome showed that the subject’s shoulder range of motion (ROM), Disabilities of the Arm, Shoulder and Hand (DASH) score and pain improved remarkably, enabling Ms X to resume post-stroke rehabilitation and reduce her analgesic intake.

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  • Research Article2020-08-01

    Wet Cupping Therapy Improves the Parameters of Ventricular Repolarization

    Mustafa Çelik 1, *, Hasan E. Yücel 2, Serkan Sivri 1, Erdogan Sökmen ? 1, Cahit Uçar 2

    Abstract : Background: Cupping therapy (CT) is an ancient medical treatment since antiquity and is used for the treatment of such various disease states as contagious diseases, chronic or acute inflammatory disease, and autoimmune disorders. Ventricular repolarization is represented by QT and corrected-QT (QTc) intervals from surface electrocardiography. Objectives: As novel repolarization parameters, Tpeak-toTend (Tp-Te) interval, and Tp-Te/QT and Tp-Te/ QTc ratios are suggested to correlate better with ventricular arrhythmia risk in various clinical conditions than sole QT and QTc intervals. In this study, we aimed to determine whether these parameters changed significantly after CT in healthy individuals. Methods: One hundred and twenty participants (57 women and 63 men; mean age: 49.0 ± 13.0 years) participated in this study. ECGs strips were recorded 1 hour before and 1 hour after CT from each participant, and relevant ECG parameters were compared. Results: Tp-Te interval [69.51 ± 11.54 msec vs 63.15 ± 10.89 msec, p = 0.001], Tp-Te/QT ratio [0.191 ± 0.030 vs 0.174 ± 0.031, p = 0.002] and Tp-Te/QTc ratio [0.175 ± 0.030 vs 0.159 ± 0.026, p = 0.001] were found to be significantly decreased 1 hour after the procedure compared with the pre-procedure values. However, no statistically significant change was observed in mean heart rate, QT and QTc intervals, QT/ QRS and cQT/QRS, and frontal QRS/T angle after the procedure compared with the same parameters before the procedure (p > 0.05). Conclusions: In accordance with the results of our study, it is plausible to conclude that CT may exert cardioprotective effect. However, larger scale prospective studies are needed to support our findings.

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  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS

    Abstract : Emerging data indicates that not all chronic pain patients with a given diagnosis have the same underlying pathophysiology. This is particularly relevant for the widespread pain condition known as fibromyalgia (FM) wherein existing pharmacologic and non-pharmacologic treatments are suboptimal: only 30-40% of patients have a clinically meaningful reduction in their pain. Varying degrees of pain pathophysiology are also likely relevant for acupuncture as thousands of patients are often needed to determine statistical significance between sham and verum groups in randomized controlled clinical pain trials. I will present data suggesting that quantitative sensory testing and needling sensations obtained at baseline, can be used to identify different biotypes of FM patients that respond differentially to sham and verum acupuncture. More sensitive FM patients respond better to sham acupuncture whereas less sensitive patients respond better to verum. This type of data could improve clinical trial power by selectively identifying the right type of patient at baseline that is likely to respond to the right type of acupuncture treatment. Thus supporting a more personalized approach to the treatment of chronic pain with acupuncture.

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  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS

    Abstract : Objectives After the development of Sasang constitutional theory by Dr. Lee Jema, there were several kinds of Acupuncture theory in Korea. In this topic we’d like to look over methods of each treatments to find out better solutions. Methods 1) Outline of each treatments 2) Try to find out the problems in their theory Results 1) There are some problems in their visceral concept application between meridian theory and Sasang constitutional theory. 2) In the case of constitutional acupuncture treatments of Dr. Kwon’s and Dr. Yom’s, they had to provide reasons of choosing different pulse positions as oppose to traditional pulse positions. 3) Differentiating standard for constitution classification based on pulse diagnosis is too subjective. Conclusion We have to try to find out better solutions to cover such problems.

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  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS

    Abstract : Glandular trichomes are known to be the sites of cannabinoid accumulation in Cannabis sativa. They cover the surface of the aboveground plant parts but are most abundant on the floral bracts of pistillate plants. This study conducted to determine where the cannabinoids are synthesized and localized at the whole-plant level and at the cellular level using micromanipulation and transmission electron microscopy. According to their external features, three types of glandular trichomes are recognized: bulbous, capitate-sessile, and capitate-stalked trichomes. The gland head consist of disc cells containing cytoplasm and a non-cellular intrawall secretory cavity. The lipoplasts in the disc cells of globose heads synthesize lipophilic terpenes that migrate through the plasma membrane and into the cell wall adjacent to the secretory cavity. They subsequently pass through the cell wall and accumulate in the secretory cavity in the form of secretory vesicles. Numerous vesicles of different sizes and densities are localized in the secretory cavity. In conclusion, lipophilic terpenes and phenols, when released from their respective lipoplasts and vacuole compartments, accumulate in the plasma membrane/cell wall interface, where enzymes combine these precursors into cannabinoids. Mature glands possess the highest concentration of major cannabinoids, such as CBD in the fiber strains and THC in the drug strains of Cannabis sativa.

    Abstract

Journal Info

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
February, 2021
Vol.14 No.1

pISSN 2005-2901
eISSN 2093-8152

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  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01

    Abstract : Respiratory inflammation is a frequent and fatal pathologic state encountered in veterinary medicine. Although diluted bee venom (dBV) has potent anti-inflammatory effects, the clinical use of dBV is limited to several chronic inflammatory diseases. The present study was designed to propose an acupoint dBV treatment as a novel therapeutic strategy for respiratory inflammatory disease. Experimental pleurisy was induced by injection of carrageenan into the left pleural space in mouse. The dBV was injected into a specific lung meridian acupoint (LU5) or into an arbitrary non-acupoint located near the midline of the back in mouse. The inflammatory responses were evaluated by analyzing inflammatory indicators in pleural exudate. The dBV injection into the LU5 acupoint significantly suppressed the carrageenan-induced increase of pleural exudate volume, leukocyte accumulation, and myeloperoxidase activity. Moreover, dBV acupoint treatment effectively inhibited the production of IL-1β, but not TNF-α in the pleural exudate. On the other hand, dBV treatment at non-acupoint did not inhibit the inflammatory responses in carrageenan-induced pleurisy. The present results demonstrate that dBV stimulation in the LU5 lung meridian acupoint can produce significant anti-inflammatory effects on carrageenan-induced pleurisy suggesting that dBV acupuncture may be a promising alternative medicine therapy for respiratory inflammatory diseases.

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  • Research Article2020-02-01

    Abstract : This study investigates whether visual deprivation influences participants' accuracy in differentiating between real and sham acupuncture needles. It also evaluates the relative contributions of tactile, visual, and auditory cues that participants use in their decision-making processes. In addition, a simple sensory decision-making model for research using acupuncture sham devices as comparative controls is proposed. Forty healthy individuals underwent two conditions (blindfolded and sighted) in random sequence. Four sham and four real needles were randomly applied to the participants' lower limb acupoints (ST32 to ST39). Participants responded which needle type was applied. Participants then verbally answered a questionnaire on which sensory cues influenced their decision-making. The proportion of correct judgments, P(C), was calculated to indicate the participants' accuracy in distinguishing between the needle types. Visual deprivation did not significantly influence the participants' discrimination accuracy. Tactile cues were the dominant sensory modality used in decision-making, followed by visual and auditory cues. Sharp and blunt sensations were associated with the real and sham needles, respectively, for both conditions. This study confirmed that tactile cues were the main sensory modalities used in participant decision-making during acupuncture administration. Also, short-term blindfolding of participants during procedures will unlikely influence blinding effectiveness. Clinical trial registration number Not applicable. This study does not fall under the definition of a clinical trial under the ICMJE guidelines.

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  • Impact Shot2020-10-01

    Herbal Transformation by Fermentation

    Chang-Gue Son 1, *, Sam-Keun Lee 2, In-Kyu Choi 2, Eun-Su Jang 1, Kee-Jung Bang 3

    Abstract : We herein show a dramatic change of herbal properties of the composition as well as function via fermentation of Cynanchi atrati Radix (family Asclepiadaceae). Cynanchi atrati Radix showed a high cytotoxicity against B16-F10 melanoma cell line, but the function of Cynanchi atrati Radix was completely changed into anti-melanin activity at very low concentration after Lactobacillus -fermentation. In addition, the compounds were drastically changed as shown in HPLC-based profile. Furthermore, this transformation has been achieved by only Lactobacillus -fermentation. This study proposes an strategy which we need to consider in the herb-derived material researches including pharmacopuncture.

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  • Research Paper2020-10-01

    The Effects of Auriculotherapy on Shoulder Pain After a Cesarean Section

    Abedini Maryam 1, Aminzadeh Fariba 2, Manshoori Azita 2, Bakhtar Babak 3, Sadeghi Tabandeh 4, *

    Abstract : Background: Postcesarean section shoulder pain caused by constrained upper extremity movement limits the maternal activities of breastfeeding and neonatal care. Objectives: This study aims at investigating the effects of auriculotherapy on shoulder pain after a cesarean section. Methods: In this randomized controlled trial, 90 candidates for a cesarean section were selected according to the inclusion and exclusion criteria and randomly allocated into control and intervention groups by the minimization method. In the intervention group, ear seeds were placed on shoulder and muscle relaxation points from two hours prior to surgery until 24 hours after it. In the control group, ear seeds were placed on placebo points. Shoulder pain was assessed on a numerical pain scale in 1, 6, and 24 hours after surgery. Results: There was no significant difference between the two groups 1 and 6 hours after surgery. However, there was a significant difference between the two groups 24 hours after surgery and the mean pain score was lower in the intervention group (independent t-test, p < 0.001). Conclusion: The use of auriculotherapy is recommended for the prevention and alleviation of shoulder pain after a cesarean section.

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  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01

    Abstract : With thousands of years evolution, the human body has developed self-healing properties to recover from disorders. Theoretically, many alternative medicines may work to activate / enhance this self-regulation process. In my talk, I will introduce recent studies on the effects and brain mechanisms of acupuncture, mind-body exercise (Tai Chi and Baduanjin), and imagery on both experimental and chronic pain. Findings of these studies suggest that different alternative interventions may share a common network through which to relieve pain.

  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01

    Abstract : Sports injuries are very common, not only among professional athletes, but moreso among those professionals and students who would like to maintain an active lifestyle but only have time during weekends for their favorite sports. These athletic injuries may range from minor sprains to actual muscle tears that require weeks of anti-inflammatory treatment. Age-old acupuncture and moxibustion techniques can actually provide better and faster pain relieving methods that can also facilitate healing with minimal intervention. After the initial application of sports medicine protocols for the acutely injured athlete, immediate daily follow up treatments with moxybustion and acupuncture helps in getting the athlete back to training earlier and more comfortably than any medication currently employed by the conventional physiatrist. A perfect example of the multiplicatory effect of east meets west in the field of sports medicine.

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