전체메뉴
Search
Article Search

JoP

Most Downloaded

  • Abstract : Role of electroacupuncture (EA) in refractory unilateral sensorineural hearing loss (SNHL) remains unclear but might be promising for the Meniere's disease. Two cases of unilateral SNHL who were unresponsive to conventional treatment of sudden SNHL showed complete recovery after receiving EA therapy. The first case was a 46-year-old woman who received EA in the seventh month after the acute onset of sudden right hearing loss and tinnitus. She had mild-to-moderate degree of SNHL at high frequencies in the right ear with episodic vertigo. The second case was a 55-year-old woman who received EA in the sixth year after developing sudden SNHL in the right ear. Before the EA began, her pure tone average of the affected ear was 45 dB and the phonetically balanced score was 88%. The regimen for both patients included 12 sessions of EA over four weeks at the main acupoints (Tinggong (SI 19), Ermen (TE 21), Qimai (TE 18) and Yifeng (TE 17) on the affected ear and the adjuvant acupoints (Zhongzhu (TE 3), Hegu (LI 4), Qihai (CV 6), Guanyuan (CV 4), Taixi (KI 3), and Taichong (LIV 3)). Both patients regained their normal hearing thresholds three weeks after the first EA. No adverse events were observed. Hence, EA may be a useful additional therapy in unilateral SNHL, even at the late phase when other treatments have failed because the possibility of Meniere's disease cannot be excluded.

    Abstract
  • Research Article2020-08-01

    Abstract : Background: The primo vascular system (PVS) is a novel network composed of primo nodes (PNs) and primo vessels (PVs). Currently, its anatomy is not fully understood. Objectives: The aim of this study was to elucidate the three-dimensional PNePV structure. Methods: Organ-surface PVS tissue was isolated from healthy and anemic rats. The tissues were analyzed by X-ray microcomputed tomography (CT), hematoxylin and eosin staining, and scanning electron microscopy. Results: From CT images, we identified one or more bundles in a PV. In the PN, the bundles were enlarged and existed in isolation and/or in anastomosis. The transverse CT images revealed four areas of distinct intensities: zero, low, intermediate, and high. The first two were considered to be the sinuses and the subvessels of the PVS and were identified in the hematoxylin and eosinestained PN sections. The enlargement of the PN from anemic rats was associated with an increase in the intermediate-intensity area. The high-intensity area demarcated the bundle and was overlapped with the mesothelial cells. In scanning electron microscopy, the PV bundles branched out, tapering down to a single bundle at some distance from the PN. Each bundle was composed of several subvessels (~5 µm). Clustered round microcells (1-25 µm), scattered flat oval cells (~15 µm), and amorphous extracellular matrix were observed on the surface of the PVS tissue. Conclusions: The results newly showed that the primo bundle is a structural unit of both PVs and PNs. A bundle was demarcated by high CT intensity and mesothelial cells and consisted of multiple subvessels. The PN bundles contained also sinuses.

    Abstract
  • Research Article2020-06-01
    JAMS

    Abstract : ObjectivesThe aim of this study is to determine the effect of acupressure on the severity of pruritus and some laboratory parameters in patients undergoing hemodialysis.Materials and MethodsThe present clinical trial was conducted on 90 hemodialysis patients. Pressure was applied on SP6, SP10, ST36, and LI11 points in the intervention group and on ineffective points for the sham control group. The severity of itching was measured using the Numeric Rating Scale.ResultsThere was a significant reduction in the severity of pruritus over the course of the study in the intervention and sham control groups (P=0.001). Also significant differences were observed at the end of the intervention in terms of serum phosphorus (P=0.045) and parathyroid hormone (P=0.004) levels between groups.ConclusionAcupressure can improve the severity of pruritus dramatically in hemodialysis patients, but has no effect on laboratory parameters, except for serum phosphorus and parathyroid hormone levels.

    Abstract
  • Abstract : The primo vascular system (PVS) has been difficult to detect due to its small diameter and translucent features of the thread-like network. Thus, the developed methods to find and take out PVS were to use contrast-enhancing dyes including Alcian blue, Trypan blue, and Janus green B. To use as a detector to PVS and a biological tool for functional study of PVS, monoclonal antibodies (mAbs) against PVS of rat were generated by various techniques, such as cell fusion, enzyme-linked immunosorbent assay (ELISA), Western blotting (WB), screening of hybridoma, immunofluorescence microscopy (IF). Among 16 mAbs generated, 4 representative mAbs were characterized with their specificities in ELISA, WB, and IF. α-rPVS-m1-1 and α-rPVS-m4-6 had strong binding affinities to PVS in both ELISA and WB but did not show specificities at all in IF. On the contrary, α-rPVS-m3-2 and α-rPVS-m3-4 almost did not respond in WB but had strong binding affinities in ELISA and specificities in IF. Two mAbs stained predominantly at extracellular matrix and cell membrane of PVS of rat in IF. Thus, α-rPVS-m3-2 and α-rPVS-m3-4 can be used as a tool in discriminating PVS from blood vessel (BV) and lymphatic vessel (LV) and other similar tissues of rat in IF.

    Abstract
  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS

    Abstract : Objectives Knee pain is the illness that has ranked top in the medical cost and visit number in the Korean Medicine (KM) institutions. With the trend that the older aged population is increasing, it is predicted that people with knee pain is increasing resulting in the life quality degradation and the high social costs. In this situation, KM has strength in the clinical practice of knee pain. The purpose of Clinical Practice Guideline (CPG) was to enhance the reliability of KM by reinforcing the evidence with objective and rational verification, to develop a standardized clinical guideline, and to make a reasonable judgment in the treatment of knee pain. Methods We assembled committee with experts and established development plan. Committee set up key questions and searched relevant evidence comprehensively by using following databases: Pubmed, Ovid-EMBASE, Cochrane library, CNKI, OASIS, and NDSL. The evidence were reviewed according to the pre-defined selection/exclusion criteria, and the guideline draft was made by using the quality of evidence (4 levels: High, Moderate, Low, and Insufficient) and the grade of recommendation (5 grades: A, B, C, D, and GPP) based on the GRADE method. Official consensus was obtained through the following steps: 1) we used the Delphi method to reach agreement on the draft. 2) draft was further revised through external review and produced into the final guideline. 3) guideline obtained confirmation from relevant academic societies. Results We classified knee pain into 4 categories (knee osteoarthritis, knee rheumatoid arthritis, soft tissue injury, and other type) and made guideline according to several KM treatments (e.g. manual acupuncture, electroacupuncture, warm or fire needle acupuncture, moxibustion, herbal medicine, pharmacopuncture, acuputomy, cupping, and others). Among them, it was confirmed that pharmacopuncture had moderate evidence and B recommendation level (high considerable) on knee osteoarthritis. To complement the existing CPG published in 2017, we will expand KM treatments (e.g. physiotherapy, chuna, and manipulation therapy), focus on the disease name (e.g. knee osteoarthritis not knee pain), and create evidence through direct execution of randomized clinical trial. Conclusion CPG is expected to provide objectivity, rationality, and standard of KM treatment for knee pain by continuous research and supplementation.

    Abstract
  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS

    Abstract : Objectives To evaluate the quality and validity of clinical practice guidelines (CPGs) which include the strength of recommendation on acupuncture in Japan. Methods The relevant CPGs were searched and selected according to predefined criteria, and reviewed by three independent researchers in terms of methodology and correctness. Results As of July 2019 in Japan, there were 13 CPGs including statements on the strength of recommendation on acupuncture. Among them, 2 CPGs were in accordance with the GRADE system, and 9 were rated as 4 or less (7-point scale) in the overall ratings with AGREE II. Regarding consistency with predefined methods of formulating recommendations, acupuncture is underestimated in 3 CPGs (facial palsy, chronic headache and irritable bowel syndrome). Also, 2 CPGs (lateral humeral epicondylitis and interstitial cystitis) published in 2006 and 2007 were out-of-date. Recently published “Japanese Orthopaedic Association (JOA) Clinical Practice Guidelines on the Management of Low Back Pain 2019” included multiple issues of serious misinformation on acupuncture: the opposite and incorrect conclusions that acupuncture is not superior to the control group, due to errors in literature selection, data extraction and data input. Conclusion Overall, the quality of CPGs assessing acupuncture as a treatment option are not necessarily high in Japan, and some of the CPGs need to be revised. Validation of CPGs including information on acupuncture should be conducted periodically. Exchanging information among countries in this issue would be useful and encourage this continuous work.

    Abstract
  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS

    Abstract : Saam acupuncture (SA) is a unique acupuncture treatment based on traditional Korean medical principles. The traditional theory about yin and yang, five elements, meridians are used in the application of SA. In particular, it uses the combination of five shu points for deficiency and excess of the meridians. After the diagnosis is made, the doctor principally selects four acupuncture points located below the elbow and knee joint and this makes SA an especially convenient and strong effective tool to patients. SA is a popular and safe treatment intervention widely applied in clinical practice to manage various conditions including musculoskeletal pain, mental disorder, and chronic, functional diseases. There are several previous studies related to SA for peripheral neuropathy, hwa-byung, amyotrophic Lateral Sclerosis, and so on. Pubmed and Korean databases were searched for clinical studies about SA treatment, and published articles related to SA and clinical trials, case studies are presented in this review.

    Abstract
  • International Scientific Acupuncture and Meridian Symposium (ISAMS) 2019 Conference Abstracts2020-04-01
    JAMS

    Abstract : Taegeuk acupuncture treatment which was suggested by Dr. Lee Byung-haeng for the first time in 1974, is based on Korean original Constitutional theory, Sasang Constitutional Medicine. In Dongeui-Susebowon, written by Dr. Lee Jema in 1894, he emphasized the function of heart by saying that heart is Taegeuk at the center among the five viscera organs and rules the other four organs. The name Taegeuk acupuncture was originated from the importance of heart as Taegeuk in Dr. Lee Jema's theory. Sasang Constitution means four types of constitution comprised of Tae-Yang, So-Yang, So-Eum and Tae-Eum. Tae-Yang has a characteristic of metal, So-Yang is fire, So-Eum is water, and Tae-Eum is wood. There are three main acupuncture points related to different charicteristics and dominant organ functions of each constitution. One is among Heart meridian five shu points, and it is used for reinforcing method to restrain the dominant characteristic of each constitution. Another point is yuan-source (primary) point on the weak organ's meridian for reinforcement. The other is yuan-source (primary) point on the strong organ's meridian for reduction. For instance, in case of Tae-Yang, by reinforcing HT8 which has a characteristic of fire among heart meridian five shu points, we can reduce excessive metal-dominant characteristic of Tae-Yang. Since Tae-Yang has a decreased function of liver system, we choose LR3 for reinforcement, and LU9 for reduction of an excessive function of lung system. Therefore, the three main acupuncture points for Tae-Yang consist of HT8(+), LR3(+), and LU9(-). In a clinical practice, LI4, LI11 and ST36 are additionally chosen as representatives of acupoints on the upper and lower extremity. However, the treatment effects seem similar whether or not you choose the three additional points. Therefore, when you treat pediatric patients or patients who are afraid of needles, you can use only the three main points for the treatment. Its clinical applications are psychogenic diseases (e.g. anxiety, depressive mood disorder, Hwa-byung, sleep disorder, etc.), autonomic nerve system disorders, poor blood circulation, chronic pain syndrome (e.g. fibromyalgia), chronic fatigue syndrome, and so on. It can be an effective treatment measure for refractory conditions which show poor response to conventional treatments and other acupuncture techniques. This is because, Taegeuk acupuncture helps patients' own natural healing process by restoring the balance of the human body, regardless of the locations or etiology of the illness. When you have the patient who has one of those conditions listed above, the first thing you have to do is examining epigastric tenderness and hepatic dullness, to identify the patient's constitution before the practice of acupuncture. Correct classification of the constitution is the most important part of the treatment process. Dr. Lee Jema suggested the classification of the four constitutions based on the personality and external appearance. In addition to Dr. Lee Jema's theory, Dr. Lee Byung-haeng checked the response of the patient after treating one point among Heart meridian five shu points which restrains the dominant characteristic of assumed constitution. However, because sometimes the patient's personality, appearances, and response to acupoint needling are not typically fit into one specific constitution, it is not easy to identify one's constitution with those methods. As a solution, we can check epigastric tenderness and hepatic dullness sound before and after performing probable types of acupuncture on the patient. If you performed the correct type of acupuncture (your classification of the constitution was correct), epigastric tenderness and hepatic dullness get better after the treatment. Thus, epigastric tenderness and hepatic dullness can be diagnostic indices before the treatment as well as effect estimation indices during the course of treatment.

    Abstract

Journal Info

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
February, 2021
Vol.14 No.1

pISSN 2005-2901
eISSN 2093-8152

Archive >

Editorial Office

Most Read / Downloaded

  • Research Article2020-08-01

    Abstract : Background: Uremic pruritus is a common boring complaint in patients suffering from chronic renal failure. Owing to cost and the side-effects of medications, complementary therapies are more attractive for pruritus treatment. Objectives: The aim of this study is to determine the effect of acupressure on the severity of pruritus and some laboratory parameters in patients undergoing hemodialysis. Materials and methods: The present clinical trial was conducted on 90 patients undergoing hemodialysis who were allocated in intervention, sham control, and negative control groups (30 in each group). Pressure was applied on SP6, SP10, ST36, and LI11 points in the intervention group and on ineffective points for the sham control group. The negative control group received routine care. The severity of pruritus was measured using the numeric rating scale before, two weeks, and five weeks after intervention. The laboratory parameters were measured before and after the intervention. Results: There was a significant reduction in the severity of pruritus over the course of the study in the intervention and sham control groups (p = 0.001). In addition, significant differences were observed at the end of the intervention in terms of serum phosphorus (p = 0.045) and parathyroid hormone (p = 0.004) levels between groups. Conclusion: Acupressure can improve the severity of pruritus dramatically in hemodialysis patients. It can also reduce serum phosphorus and parathyroid hormone levels, which affect pruritus, significantly. Therefore, this simple and inexpensive intervention may be recommended for reducing uremic pruritus among patients undergoing hemodialysis.

    Abstract
  • Research Article2020-06-01

    Effectiveness of Acupuncture in Dental Surgery: A Randomized, Crossover, Controlled Trial

    Maria L.B. Gil 1, *, Luide M.R.F. Marinho 2, Márcio de Moraes 2, Ronaldo S. Wada 1, Francisco C. Groppo 3, Jorge E. Sato 4, Maria L.R. de Sousa 1, **

    Abstract : Objectives: The objective of this crossover clinical study was to evaluate the effectiveness of Energy Regulation with Acupuncture in clinical occurrences in impacted lower third molar surgeries. Methods: The sample consisted of 22 patients with two impacted third molars, in symmetrical position; divided into two groups: Test Group (TG) with Real Energy Regulation Group and Sham Group (SG) with Acupuncture without Energy Regulation function. The extraction was performed 30 days apart. Energy flow (Ryodoraku Method) and energy regulation performed before extraction were measured. Heart Rate (HR) and Blood Pressure (BP) were evaluated before and after energy regulation and after surgery, residual edema was measured by facial measurements (angle of the mandible to tragus (A-T); angle of the mandible to labial commissure (A-LC); angle of the mandible to the wing of the nose (A-WN); angle of the mandible to the corner of the eye (A-CE); angle of the mandible to the chin (A-C); and mouth opening by the interincisal distance, before and after seven days of surgery. To quantify intraoperative bleeding (ml), blood was aspirated along with the saline solution using a portable vacuum pump adaptor. The amount of saline solution used was subtracted from the final amount of aspirated fluid. Results: Mean of bleeding was lower in TG (p = 0.0392). There were significant differences between groups in facial distances: A-LC (p = 0.010), A-WN (p = 0.030) and A-C (p = 0.008). Conclusion: Energy regulation with real acupuncture was effective in reducing postoperative residual edema and intraoperative bleeding.

    Abstract
  • Erratum2020-12-01
All Newest Articles
  • 2020-04-01
  • Research Paper2019-08-01

    Effects of Acupressure on Fatigue in Patients with Cancer Who Underwent Chemotherapy

    Atefeh Ghanbari Khanghah1, Moloud Sharifi Rizi2*, Bahram Naderi Nabi3, Masoumeh Adib4, Ehsan Kazem Nejad Leili5

    Abstract : Fatigue is the commonest symptom in cancer patients; despite high levels of clinically significant persistent cancer-related fatigue, few treatments are currently available. The aim of this study was to evaluate the efficacy of acupressure on fatigue in patients with cancer who underwent chemotherapy. The study was designed as a randomized and controlled trial. Ninety samples were selected using the convenience sampling method, and random block sampling was used for allocation of groups (30 for each group). The three groups were similar by age and gender. The experimental group underwent acupressure at the Zusanli (ST-36), Hegu (LI-4), and Sanyingjiao (SP-6), whereas sham pressure was used in the placebo group and no intervention was applied in the control group; the level of fatigue of participants in three groups was calculated in three phases, before, during, and after chemotherapy. Data were analyzed using SPSS, version 22. The results showed that the mean of visual analog score of fatigue is significantly different in three groups at the end of chemotherapy (p = 0.021). The mean visual analog score of fatigue in the acupressure group was meaningfully lower than that in the control group after chemotherapy (p = 0.028). Results of this investigation showed that acupressure has short-term effectiveness on the cancer-related fatigue of patients undergoing chemotherapy.

    Abstract
  • Erratum2020-12-01
All Newest Articles

Scimago Journal & Country Rank

SCImago Journal & Country Rank